What types of OTC medications help with painful plaques? Looking for an OTC lotion or treatment for painful, burning skin plaques. What has worked for you? By RebeccaB · August 31, 2017 SHARE Email Created with Sketch. Comment Created with Sketch. 0 Heart Community Answers Share Your Answer Join the conversation! Log in or create an account. Poll Recommended Reading Other Types Of Psoriasis by Editorial Team Living With Autoimmune Disease by Editorial Team Psoriasis Hits Me Right in the Feels by Chris Pettit Strangest Psoriasis Symptoms by KTVanHorn