Bryhal (halobetasol propionate) Lotion

Reviewed by: HU Medical Review Board | Last reviewed: September 2023 | Last updated: September 2023

Bryhali® (halobetasol propionate) lotion is a prescription topical corticosteroid treatment of plaque psoriasis in adults.1

What are the ingredients in Bryhali?

The active ingredient in Bryhali is halobetasol propionate.1

How does Bryhali work?

Psoriasis is an autoimmune condition that causes the immune system to mistakenly activate and trigger inflammation. This inflammation causes the body to make too many new skin cells, which in turn causes them to build up and form plaques.2

Topical corticosteroids like Bryhali work by decreasing inflammation and reducing the activity of the immune system. This helps reduce psoriasis symptoms.1

What are the possible side effects?

The most common side effects of Bryhali include:1

  • Burning, stinging, itching, and dryness at the application site
  • Upper respiratory tract infection
  • High blood sugar

These are not all the possible side effects of Bryhali. Talk to your doctor about what to expect when taking Bryhali. You also should call your doctor if you have any changes that concern you when taking Bryhali.

Other things to know

Before starting treatment with Bryhali, tell your doctor if you have:1

  • Irritation or other skin reactions to a steroid medicine in the past
  • A skin infection
  • Diabetes
  • Adrenal gland problems
  • Liver problems

There is not enough data to know if Bryhali is safe to take while pregnant or breastfeeding. Before starting treatment with Bryhali, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. They can help you decide if Bryhali is right for you.1

Do not use Bryhali on your face, groin, or underarms.1

Do not bandage, wrap, or cover the treated skin areas unless your doctor tells you to.1

Wash your hands after using Bryhali, unless you are using the medicine to treat your hands.1

Talk to your doctor if your skin does not improve after 8 weeks of treatment with Bryhali.1

Bryhali can interact with other medicines. Before starting treatment with Bryhali, tell your doctor if you take other corticosteroids, medicines by mouth or injection, or use other products on your skin that contain corticosteroids.1

Before beginning treatment for psoriasis, tell your doctor about all your health conditions and any other drugs, vitamins, or supplements you are taking. This includes over-the-counter drugs.

For more information, read the full prescribing information of Bryhali.

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