Hi Mike1958. On top of the excellent information on biologics provided by Victoria, thought you might also be interested in this article from our editorial team on combination therapy: https://plaquepsoriasis.com/clinical/combination-therapy/. For your protection, we cannot provide medical advice over the internet, but it may be something for you to ask your doctor about. Keep us posted on how you are doing. Best, Richard (PlaquePsoriasis.com Team)