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Psoriasis and Keytruda

Keytruda caused my psoriasis to cover 60% of body. Has anyone ever experienced this? Local Dermitologists no clue.

  1. Hi , thank you so much for reaching out to the community here. I don't have personal experience with this, but I hope anyone who does will stop by to share with you. It's not uncommon for psoriasis to be triggered by other medications, although I had not heard of Keytruda prior to your post. I did a quick internet search and found quite a few reports of Keytruda/pembrolizumab-induced psoriasis. Here's one such case study, which also talks through how this person's medical team decided to deal with this issue:

    It sounds like you've already been through such a lot with your health. I'm sorry that this psoriasis flare has added to your struggles. Did you have psoriasis before this? And have your doctors made any suggestions as to how to manage this going forward? I sincerely hope that there's a way for you to find the relief you deserve. Please keep us updated, and do reach out if you need support or have any further questions - we'll do our best to help! Warmest wishes, -Catherine, Community Moderator

    1. This is a new one for me also as I have never heard of this. Based on my research, Keytruda is primarily used to treat certain types of cancer by helping the immune system identify and attack cancer cells. If you have other health conditions, the medication may have triggered or exacerbated inflammatory skin conditions that could have contributed to psoriasis-like symptoms. There are so many questions that need answering regarding your health before taking this treatment to now that only would be able to take a deep dive to see exactly what has happened. Have you also mentioned this with your PCP? I hope you get some answers soon. All the best, -Latoya (Team Member)

      1. Hello , I guess my first question did you already have psoriasis, and did this drug make it worse? Does psoriasis run in your family? I did stop a medication once that caused me to have a horrible flare, but this is not what you are talking about. Psoriasis flares are no fun at all. Let us know what you find out. We would love to hear from you. Diane (Team Member)

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