, I've often wondered if anyone else has had this happen! My experiences past and present - Dovobet ointment worked on my knees, Dovonex helps on my elbows, an OTC cream called Dermalex worked on my feet, almond oil seems to soothe psoriasis on my face, coal tar eases my scalp psoriasis, UVB helped my guttate and inverse psoriasis, methotrexate made a difference to all my psoriasis (until the psoriasis got triggered again) apart from a patch on my thigh. The patch on my thigh didn't respond to anything for YEARS and then suddenly it just vanished by itself, with no new/additional treatment, a couple of months ago. All of these treatments helped with a specific area of psoriasis and either made no, minimal or short-lived differences everywhere else. It's so strange that this happens! Especially so with the systemic medications like biologics or methotrexate - one would think they would have the same impact over the whole body! -Catherine, Community Moderator