I have had plaque psoriasis for 30+ years, but 5 yrs ago it got to the point where it was SEVERE (every major part of my body was engaged, and my legs and torso were extreme). I finally got the courage to try a biologic and went on Cosentyx for 3 years. For 2 1/2 years, I was 100% clear!!!!!!!!! It was a miracle!!! Not a single inch of plaque. My nails cleared, my scalp cleared and my entire body was mine again... I became a real human for the first time in decades. And by the way, not a single solitary side effect either. However, after 2 1/2 years, it just started coming back... fast and furious. I am now, once again, looking like a Grey-Scale victim from Game of Thrones, and am going to try Trymfya. I'll keep everyone up to date. But as for Cosentyx... it gave me 2 1/2 years of bliss that I will remember for the rest of my life.